A RANDOMIZED, NON-INFERIORITY STUDY COMPARING EFFICACY AND SAFETY OF A SINGLE DOSE OF PEGFILGRASTIM VERSUS DAILY FILGRASTIM IN PEDIATRIC PATIENTS AFTER AUTOLOGOUS PERIPHERAL BLOOD STEM CELL TRANSPLANT.

PurposeTo assess the non-inferiority of pegfilgrastim versus filgrastim in speeding the recovery of polymorphonuclear cells (PMN) in pediatric patients who underwent autologous peripheral blood stem cell transplant (PBSCT).MethodsThe sample size of this randomized, multicenter, phase III study, was calculated assuming that a single dose of pegfilgr

We explored the interaction between radiation of different wavelength and jasmonic acid (JA) or brassinosteroids (BR) on leaf senescence-induced oxidative stress.Three approaches were used: 1) jasmonic acid insensitive1-1 (jai1-1) taotao gk110 go kart parts and brassinosteroid-deficient [dumpy (dpy)] mutants were treated with red (R) or far-red (FR

Leishmaniasis is a vector-borne disease caused by the protozoan parasite of Leishmania genus and is a complex disease affecting mostly tropical regions of the world.Unfortunately, despite the extensive effort made, there is no vaccine available for human use.Undoubtedly, a comprehensive understanding of the host-vector-parasite interaction is subst

Spontaneous spinal epidural hematoma (SSEH) is an uncommon condition that can lead to severe neurological injuries, often accompanied by back pain.Pregnancy is identified as a risk factor for SSEH.Early diagnosis of SSEH presents challenges due to its atypical manifestations and the use of intraspinal anesthesia and analgesic techniques.In this cas